The San Francisco 49ers have been dominant at 9-2 ATS in their last 11 games against the Arizona Cardinals as those two NFC West teams meet on the gridiron on Sunday afternoon.
The Niners are also 10-1-1 ATS in their last 12 games as road favorites, but just 3-8 ATS in their last 11 games on the road against fellow NFC West teams.
The Cardinals have performed well as home underdogs lately, going 7-3 ATS in their last 10 games in that situation.
San Francisco 49ers vs Arizona Cardinals Sportsbook Odds and Betting Line
Betting fans looking to side with the Arizona Cardinals in this one found them as 2-point underdogs earlier in the week at Sportsbook, while the total was sitting at 42.5 over at Sportsbook.
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Computer Prediction: San Francisco 49ers vs Arizona Cardinals Pick
Odds Shark score prediction models pick a 29-28 result in favor of the Cardinals on Sunday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.
San Francisco 49ers vs Arizona Cardinals Odds and Stats.
Team Betting Records & Power Rankings
This season the Arizona Cardinals are 2-0 overall and 1-1 ATS against the spread, while the 49ers are 1-1 and 1-1 ATS. As for the totals, Arizona is 0-2 on the OU, and San Francisco is 1-1. Stay Informed: follow us on Twitter for odds specials, betting line moves and Arizona vs San Francisco injuries news.
The power rankings show a disparity between these teams, with the Arizona Cardinals rated this week at No. 4 and the San Francisco 49ers sitting at No. 8.
How San Francisco 49ers vs Arizona Cardinals Stats Matchup
Offensively, the game matches up the Arizona Cardinals No. 21-ranked offense (21.5 PPG) against a San Francisco 49ers defense that ranks No. 18 at 22.5 PPG. The Cardinals passing attack has averaged 218 yards per game, more than the 49ers give up through the air (212.5 YPG on average).
Defensively, the San Francisco 49ers feature the league's No. 20-rated road run defense, allowing 127 yards per game. The Arizona Cardinals, meanwhile, ranks No. 17 in rushing offense at home.
Recent Outings Betting Recap
Last time out for San Francisco, they were a 28-20 loser as they battled the Bears at home. The 49ers failed to cover in the match as a -7-point favorite, while 48 combined points moved the game OVER for totals bettors. In their last game, the 49ers were Week 2 losers coming out on the wrong end of 28-20 score against Chicago.
Last time out for Arizona, they were a 25-14 Sportsbook as they battled the Giants on the road. The Cardinals covered in the match as a +2-point underdog, while 39 combined points moved the game UNDER for totals bettors. The Cardinals grabbed a Week 2 victory over the Giants in their last game, winning 25-14 at MetLife Stadium.
San Francisco 49ers vs Arizona Cardinals Betting Odds Trends
San Francisco is 9-2 SU in its last 11 games
The total has gone UNDER in 4 of San Francisco's last 5 games
San Francisco is 8-1-2 ATS in its last 11 games on the road
San Francisco is 6-1 SU in its last 7 games on the road
Arizona is 4-2 ATS in its last 6 games
Arizona is 5-1 SU in its last 6 games
The total has gone UNDER in 5 of Arizona's last 7 games
Arizona is 5-1 SU in its last 6 games at home
Next Betting Matchups
San Francisco home to Philadelphia, Sunday, September 28th
Arizona at Denver, Sunday, October 5th