Before we lay down the pick, gotta give you some opening spread numbers. Colorado opened up late Sunday night at -4 over Cincinnati and the line has jumped a point to -5.5. The Over/Under total opened up at 56.5 and has ticked up to 57.5

Cincinnati vs Colorado odds odds

Cincinnati vs Colorado, Oct. 26, 10:15 pm ET

Odds as of Oct. 23 at FanDuel

Cincinnati vs Colorado pick – Week 9

Cincinnati +5.5 (-110) at FanDuel

First we'll give you a quick swing through the coaching carousel. No one expected Coach Prime and Colorado to do anything this season, and the Buffaloes were picked to finish like 11th in the Big 12. Stop the presses. The Buffs are sitting at 5-2 and 3-1 in the conference, with a legit shot at the College Football Playoff.

On the other side of the field, Scott Satterfield came over to Cincinnati from Louisville and the results were lousy last season (3-9), but much better in 2024. Satterfield made his bones at Appalachian State where he compiled a sweet 51-24 record. At the 'Ville, he was only 25-24 and now 8-11 overall in Cincy. Giving Coach Prime a slight edge in this battle, but when it comes to commercials/endorsements, Scott S. AIN'T in the same universe as Deion!

If you're into comparative scores, check this out. Both teams played the University of Central Florida and both were winners. Just that one score was a bit lopsided. Colorado flew to Orlando and smoked the Knights 48-21. Shedeur Sanders was pretty nuts, completing 28 of 35 for 290 yards with three TDs. The other arm, Cincinnati's Brendan Sorsby was pretty sharp as well, hitting on 25 of 38 for 241 yards with one TD and two INTs.

So the at the most important position on the field, Sanders is the biggest name on the field. And is having a fantastic season, hitting on 72.2% of his passes, for 2,268 yards, with 19 TDs and six INTs. But don't sleep on Cincy's Sorsby. The kid is clicking on 67.2% of his passes, has gobbled up 1,928 air yards, with 13 TDs and 4 INTs.

And if you're worried about the status of the Buff's two-way star Travis Hunter, DON'T. Last week against Arizona, Hunter played just a half and caught only two balls. But Shedeur's other weapons were basically unstoppable. LaJohntay Wester grabbed eight for 127 yards, Will Sheppard had four for 54 yards and Drelon Miller cradled thre for 18 yards.

And some of the pressure has been relieved because they have found a rushing attack. Isaiah Augustave had 53 yards, Charlie Offerdahl had 53 and Dallas Hayden chipped in with 35. The issue with Hunter is how many snaps he will get on defense, because the Buffaloes D is pretty banged up.

Looks like the money coming in is all Buffaloes and the line has now jumped to -5.5. If the line continues to climb, gotta think about looking toward the Bearcats. Cincy has lost twice this season. A 28-27 L against Pittsburgh and a 44-41 loss at Texas Tech. So these 'Cats either win or hang to the final gun. Why? They have averaged 30.0 points per game and a very robust 451.4 total yards. If you can find a +6 or buy the hook to +6, throw a few chips at the visitors from Ohio.

Cincinnati vs Colorado betting trends