Sunday afternoon's Detroit Lions vs Dallas Cowboys Week 6 NFL matchup promises to entertain. After a dramatic victory over the Pittsburgh Steelers, Jerry Jones' Cowboys head home to meet the Lions in Arlington, Texas. Don't miss this contest from AT&T Stadium on Fox in the late window on October 13.

Explore all the Lions vs Cowboys odds and analysis on my best bets, below. 

Lions vs Cowboys Odds Week 6

Lions vs Cowboys Week 6 Picks

Lions -3

Bettor beware, the Detroit Lions have lost five straight games in Dallas. 

However, Lions are fourth in explosive play rate, while the Cowboys are 27th. Dallas sits 24th in expected points added per play allowed on defense, and 32nd in rushing EPA surrendered. 

That's a recipe for disaster against a hardnosed Detroit offense that sits third in rushing EPA, and second in rushing success rate. Dan Campbell's offense is built around their stalwart offensive line. With David Montgomery and Jahmyr Gibbs combining to devastate defenses, the Lions are extremely tough to stop. 

Additionally, Jared Goff is money indoors, going 26-9 ATS in his last 35 starts inside a dome. Dallas is vulnerable after facing a tough Steelers defense. Expect the Lions ground game to pound the Cowboys in smithereens. Back Detroit on the road as three-point favorites. 

Lions vs Cowboys Week 6 Props

Jared Goff OVER 249.5 Passing Yards -120

According to Outlier, Jared Goff has surpassed 249.5 passing yards in nine of his last 11 games. 

He averaged 277 yards per game indoors last season, while completing nearly 70% of his passes. That's carried over to 2024, where he's averaged 272 passing yards in three dome games so far. Back Goff to fly past this total in Dallas on Sunday. 

Lions vs Cowboys Week 6 Betting Trends