No. 8 Indiana welcomes reigning national champion Michigan to Bloomington on Saturday and Bet365 has the Hoosiers as a 14-point favorite and the total coming in at 49.5 points.

Before we lay down the pick, gotta give you some numbers from last season's blowout. Michigan (-32.5) was on the way to a National Championship and blew Indiana out of the water with a 52-7 crush job. That completed the hat trick for Jim Harbaugh after beating the Hoosiers 31-10 in 2022 and 29-7 in 2021.

Michigan vs Indiana Odds Week 11

Michigan vs Indiana, Nov. 9, 3:30 pm ET

Odds as of Nov. 6 at Bet365

Michigan vs Indiana pick – Week 11

Indiana -14 (-110) at Bet365

Gotta start this story with the X & O guys. Indiana's head coach Curt Cignetti has created history by leading the Hoosiers to their FIRST EVER 9-0 start! And that goes back 137 years to 1887.

Cignetti is a flat out winner everywhere he goes. He came to Bloomington from James Madison where he was 52-9 over five years and 11-1 last season. Curt has taken an IU program that was 2-10 in 2021, 4-8 in 2022 and 3-9 in 2023 to the penthouse of the the Big 10 along with Oregon.

On the other side of the field, it's all about coaching as well. As everyone who follows knows, last season Michigan won the Natty with Jim Harbaugh on the sidelines. He led the Wolverines to a 15-0 perfecto and then took a flight to L.A. to coach the Chargers.

That put Sherrone Moore in charge of the chalkboard and the results have been ugly. The win/loss record might say 5-4, but we still stand by ugly. Why? Michigan has scored 189 points and allowed 210 for a -21 point differential. Care to guess Indiana's point differential? How about +296! What? Yea, PLUS TWO HUNDRED NINETY SIX! 

How have the Hoosiers turned it around so quick? Cignetti brought a bunch of players with him from James Madison, and plucked QB Kurtis Rourke from the Ohio University Bobcats. Rourke was terrific at Ohio U. In 2022 and 2023, he hit on 65% of his passes with 36 TDs and 9 INTs. Kurtis has taken it to another level at Indiana, hitting on 154 of 210 for 2,204 yards with 19 TDs and only 3 INTs. The other arm, Michigan's Davis Warren, has been kinda MEH, with only 5 TDs and 6 INTs. YUGE advantage to the Hoosiers at the most important position on the field. 

Now we have to tell you about the revenge angle. Last season, the Wolverines embarrassed the Hoosiers in Ann Arbor, 52-7. Michigan was up 38-7 heading into the 4th Q and still tacked on 14 more points just to rub it in. OUCH! And you know what they say about pay back.

So, while we will recommend Indiana -14, we will also drop some cash on the Hoosiers to win the first half at -7.5, or, if you like, the first half moneyline. Would probably rather have the spread in the first half as opposed to the moneyline because you would have to lay $450 to win back $100. If you don't mind spending big bucks, you are probably heading in the right direction because Indiana has covered the first half moneyline in 10 of its last 11 games. And since the Hoosiers average winning margin at home this season is 35 points, we'll lay the wood. Also thinking about playing OVER 49.5 points.

Michigan vs Indiana betting trends