The 3-1 Detroit Lions face the struggling Buffalo Bills in what may be the defensive battle of the week. The Lions are ranked second in pass defense, and have held opponents to less than 81 yards per game on the ground. They have rewarded bettors with a 3-1 record ATS, while the UNDER is 6-1 in their last seven.
The 2-2 Bills burst out of the gate with a pair of victories, SU and ATS, but let an early 10-0 lead slip away in a 23-17 loss to Houston last weekend. However, Buffalo has fielded one of the NFL's best defenses against the rush, holding the Texans to just 37 yards on the ground, with four of their last five games finishing UNDER the point total.
Buffalo Bills vs Detroit Lions Sportsbook Odds and Betting Line
The Detroit Lions opened as -6.5-point favorites at odds maker shops such as Sportsbook, while the NFL total was set at 44.5 for over under totals betting.
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Computer Prediction: Buffalo Bills vs Detroit Lions Pick
Prediction-scoring formulas run on this game pick a potential 24-22 result in favor of the Lions. View the computer score prediction and who will win the pick on the moneyline for all upcoming NFL matchups here.
Buffalo Bills vs Detroit Lions Odds and Stats.
Team Betting Records & Power Rankings
Detroit bring a 3-1 record (3-1 ATS) to the Week 5 betting matchup against the 2-2 Buffalo Bills, who are 2-2 ATS against the spread. Over under betting has seen Detroit go 1-3 so far and the Bills go 0-4. Stay Informed: follow us on Twitter for odds specials, betting line moves and Detroit vs Buffalo injuries news.
The game pits the Detroit Lions, currently No. 13 in our Odds Shark NFL Power Rankings, against the Buffalo Bills, who rate No. 15 in the latest survey.
How Buffalo Bills vs Detroit Lions Stats Matchup
The game also pits Detroit's No. 23-ranked offense, averaging 21.25 PPG, against a Bills defense that ranks No. 7 this week at 18.75 PPG. The Lions aerial game is averaging 276 yards per game, more than the Bills secondary allows through the air, 266.5 YPG per game.
Defensively, the Buffalo Bills feature the league's No. 1-rated road run defense, allowing 61.5 yards per game. The Detroit Lions, meanwhile, ranks No. 24 in rushing offense at home.
Recent Outings Betting Recap
The Bills's last action saw them get a 2-TD performance from EJ Manuel, but they were handed a 23-17 loss by Houston at NRG Stadium.
Golden Tate was good for 116 receiving yards in the Lions's most recent action, helping his team to a 24-17 victory over the Jets.
Buffalo Bills vs Detroit Lions Betting Odds Trends
The total has gone UNDER in 5 of Buffalo's last 6 games
Buffalo is 3-9 ATS in its last 12 games on the road
Buffalo is 5-20 SU in its last 25 games on the road
The total has gone UNDER in 4 of Buffalo's last 6 games on the road
The total has gone UNDER in 6 of Detroit's last 7 games
The total has gone UNDER in 4 of Detroit's last 6 games at home
Detroit is 4-2 ATS in its last 6 games when playing Buffalo
The total has gone UNDER in 5 of Detroit's last 6 games when playing Buffalo
Next Betting Matchups
Buffalo home to New England, Sunday, October 12th
Detroit at Minnesota, Sunday, October 12th